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Heroin (Diacetylmorphine) is derived from the morphine alkaloid found in opium and is roughly 2-3 times more potent. A highly addictive drug, heroin exhibits euphoric (“rush”), Anxiolytic and analgesic central nervous system properties. Because heroin abusers do not know the actual strength of the drug or its true contents, they are at risk of overdose or death. Another form of heroin known as “black tar” may be sticky, like roofing tar, or hard, like coal. Its color may vary from dark brown to black.
Heroin is most often injected, however, it may also be vaporized (“smoked”), sniffed (“snorted”), used as a suppository, or orally ingested. Smoking and sniffing heroin do not produce a “rush” as quickly or as intensely as intravenous injection. Oral ingestion does not usually lead to a “rush”. But use of heroin in suppository form may have intense euphoric effects.
Heroin is metabolize to morphine and other metabolites which bind to opoid receptors in the brain. The short-term effects of heroin abuse appear soon after a single dose and disappear in a few hours. After an injection of heroin, the user reports feeling a surge of euphoria (the “rush”) accompanied by a warm flushing of the skin, a dry mouth, and heavy extremities. Following this initial euphoria, the user experiences an alternately wakeful and drowsy state. Mental functioning becomes clouded due to the depression of the central nervous system. Other effects that heroin may have on users include respiratory depression, constricted (“pinpoint”) pupils and nausea. Effects of heroin overdose may also include slow and shallow breathing, hypertension, muscle spasms, convulsions, coma, and possible death.
Other medical complications that may arise due to heroin use include collapsed veins, abscesses, spontaneous abortion, and endocarditis (inflammation of the heart lining and valves). Pneumonia may result from the poor health condition of the abuser, as well as from heroin’s depressing effects on respiration. Heroin addiction can remove an otherwise healthy and contributing member from society, and may lead to severe disability and eventually death.
Extent of Heroin Use
Heroin addiction is a treatable condition, but its use is increasing in recent years. According to the 2011 Survey on Drug Use and Health by the US Substance Abuse and Mental Health Administration, it is estimated that 607,000 persons per year used heroin in the years 2009-2011, compared to 374,000 during 2002-2005.
With regular heroin use, tolerance develops where the abuser must use more heroin to achieve the same intensity or effect. Major withdrawal symptoms peak between 48 and 72 hours after the last dose and subside after about a week.